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Dr. Joseph Mercola - Take Control of Your Health


Feb 27, 2025

Story at-a-glance

  • The brain and muscles maintain constant two-way communication — muscles release biochemical signals that travel to the brain, while the brain coordinates movement and balance
  • Regular physical activity enhances your brain function through multiple mechanisms, such as boosting neurogenesis, increasing cerebral blood flow, reducing inflammation and building cognitive reserve
  • A 2024 study revealed that both biochemical signals (myokines) and mechanical forces from muscle contractions during exercise independently contribute to motor neuron growth and development
  • Moderate-intensity exercise for at least 30 minutes is optimal for brain health, while excessive high-intensity workouts elevate cortisol and negate longevity benefits
  • Tips to tailor your routine for maximum cognitive gains are included below, such as elevating your heart rate, allowing time for results, diversifying workouts and incorporating social activities